Scientific Studies

Many studies demonstrate that the polyphenols Anthocyanins, Rutins, Quercetins, Catechins are molecules with great beneficial properties on the health.

The Role of Antioxidants in Human Health
Saikat Sen and Raja Chakraborty. Creative Educational Society’s College of Pharmacy, Kurnool, Andhra. Pradesh -518 218, India

Skin photoprotectionby natural polyphenols: Anti-inflammatory, anti-oxidant and DNA repair mechanisms
Joi A. Nichols1 and Santosh K. Katiyar (1,2,3,4). Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL. Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, AL. Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL. Birmingham Veterans Administration Medical Center, Birmingham, AL 35294, USA

Gut Microbiota Dysbiosis in Obesity-Linked Metabolic Diseases and Prebiotic Potential of Polyphenol-Rich Extracts.
Fernando F. Anhê & Thibault V. Varin & Mélanie Le Barz & Yves Desjardins & Émile Levy & Denis Roy & André Marette. Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University. Institute of Nutrition and Functional Foods (INAF), Laval University. Research Centre, CHU-Sainte-Justine and Department of Nutrition, Université de Montréal. Department of Nutrition, Faculty of Medicine, University of Montreal, Montreal.

Dietary polyphenols promote growth of the gut bacterium Akkermansia muciniphila and attenuate high fat diet-induced metabolic syndrome. Roopchand DE, Carmody RN, Kuhn P, et al.

Confirms the evidence for the prebiotic effect of polyphenol-rich extracts on Akkermansia. Diabètes. 2015.

Anthocyanins: natural colorants with health-promoting properties.
He J, Giusti MM. Department of Food Science and Technology, The Ohio State University, Columbus, Ohio 43210, USA.

Quercetin and rutin exhibit antiamyloidogenic and fibril-disaggregating effects in vitro and potent antioxidant activity in APPswe cells
Karim Jiménez-Aliaga, Paloma Bermejo-Bescós, Juana Benedí, Sagrario Martín-Aragón. Departamento de Farmacología, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n. 28040-Madrid, Spain

On the mechanism of antithromboticaction of flavonoids.
Gryglewski RJ, Korbut R, Robak J, Swies J.

The activity of medicinal plants and secondary metabolites on eosinophilic inflammation.
Rogerio AP, Sa-Nunes A, Faccioli LH. Universidade Federal do Triângulo Mineiro, Av. Getúlio Guaritá s/n, Uberaba, MG 38025-440, Brazil.

Anthocyanins and anthocyanin-rich extracts: role in diabetes and eye function

Dilip Ghosh PhD and Tetsuya Konishi PhD. Health and Food Group , The Horticulture and Food Research Institute of New Zealand Ltd., Auckland, New Zealand
Department of Functional Food Sciences, Pharmacology and Applied Life Science,Nigata University of Pharmacy & Applied Life Sciences (NUPALS), Japan

Plant polyphenols as dietary antioxidants in human health and disease
Kanti Bhooshan Pandey and Syed Ibrahim Rizvi* Department of Biochemistry; University of Allahabad; Allahabad, India

Health effects of quercetin: from antioxidant to nutraceutical.
Boots AW, Haenen GR, Bast A. Department of Pharmacology and Toxicology, Faculty of Medicine Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands.

Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections.
J Int Med Res. 2004 Mar-Apr;32(2):132-40. Zakay-Rones Z, Thom E, et al

Elderberry flavonoids bind to and prevent H1N1 infection in vitro.

Roschek B Jr, Fink RC, McMichael MD, Li D, Alberte RS. Phytochemistry. 2009 Jul;70(10):1255-61. doi: 10.1016/j.phytochem.2009.06.003. Epub 2009 Aug 12. PMID:19682714 Winston et Kuhn 2008; Hoffman 2003; Tillotson 2001; Shook 1992.

Polyphenols and prevention of cardiovascular diseases
Claudine Manach, Andrzej Mazur and Augustin Scalbert. Curr. Opin. Lipidol. 205, 16, 77-84

Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases
Khushwant S. Bhullar and H. P. Vasantha Rupasinghe. Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS, Canada B2N 5E3
Correspondence should be addressed to H. P. Vasantha Rupasinghe; Received 10 March 2013; Accepted 29 April 2013. Academic Editor: Nilanjana Maulik

Challenges for Research on Polyphenols from Foods in Alzheimer’s Disease: Bioavailability, Metabolism, and Cellular and Molecular Mechanisms.
Manjeet Singh, Madeleine Arseneault, Thomas Sanderson, Ven Murthy, Charles Ramassamy. INRS-Institut Armand-Frappier, 531 Boulevard des Prairies, Laval, Québec.

Dietary polyphenols and mechanisms of osteoarthritis
Chwan-Li Shena, Brenda J. Smithd, Di-Fan Loa, Ming-Chien Chyua,e, Dale M. Dunna, Chung-Hwan Chenf, In-Sook Kwung
Department of Pathology and Physiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA
Laura W. Bush Institute for Women's Health, Texas Tech University Health Sciences Center, Lubbock, TX, USA
Laboratory Sciences and Primary Care, Texas Tech University Health Sciences Center, Lubbock, TX, USA
Department of Nutritional Sciences, Oklahoma State University, Stillwater, OK, USA
Graduate Healthcare Engineering, Whitacre College of Engineering, Texas Tech University, Lubbock, TX, USA
Department of Orthopaedics and Orthpaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan

Bioflavonoids: proanthocyanidins and quercetin and their potential roles in treating musculoskeletal conditions.
Teixeira S. Journal of Orthoppaedic & Sports Physical Therapy 2002 Jul;32(7):357-63.

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